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Delinquent boys lack hormonal control

Drugs that stimulate the "stress hormone" cortisol might one day curb violence and aggression, research suggests

SOME young men may be aggressive because they have a reduced ability to produce a hormone that restrains violent behaviour in stressful situations.

at the University of Cambridge and his colleagues pitted young, male volunteers against virtual rivals in a provocative, stressful and frustrating video game that carried a monetary prize.

As expected, levels of the stress hormone cortisol rose in control volunteers. But in boys with “conduct disorder” – characterised by verbal and physical aggression and cruelty – levels of cortisol actually fell (Biological Psychiatry, ). The levels were similar to those of unstressed boys, says Fairchild.

He says that in most people, cortisol acts as a kind of chemical brake that restrains violent and inconsiderate behaviour, and that some types of violence are facilitated by a lack of the hormone. Drugs that stimulate cortisol might one day curb aggression in some situations.

“Drugs that stimulate cortisol might one day curb aggressive behaviour”

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