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PLACEBOS cause measurable changes in the electrical activity of the brain,
but only in patients who get some benefit from them. Psychiatrist Andrew
Leuchter from the University of California, Los Angeles, and his team gave 51
patients with depression either antidepressants or capsules containing an inert
powder. Within eight weeks, 52 per cent of the medicated patients recovered, as
did 38 per cent of the placebo group (American Journal of Psychiatry,
vol 159, p 122). Patients helped by the placebo showed increased electrical
activity in their prefrontal cortices鈥� a brain area influenced by
depression and by antidepressants. 鈥淭he placebo effect is not just 鈥榠n their
head鈥�,鈥� says Leuchter, 鈥渋t鈥檚 in their brain.鈥�